Compare four PDRN ampoules by the companion ingredient you want.
- KAHI Caviar PDRN EGF Ampoule is the direct fit for shoppers who want PDRN paired with EGF.
- Rejuran Turnover Ampoule pairs marine-based c-PDRN with hyaluronic acid for a tone-and-texture-focused formula.
- Medicube PDRN Pink Peptide Serum combines PDRN with peptides and niacinamide for a fresh, dewy feel.
- VENN Rejuvenative PDRN-NE Ampoule is a four-week hydration-focused program with 1% salmon-derived PDRN.
If you want a PDRN ampoule that pairs the ingredient with EGF, KAHI Caviar PDRN EGF Ampoule is the clearest match: KAHI describes a lightweight serum with 99% high-purity Caviar PDRN and 99% high-purity EGF in its Amazon product listing. REJURAN’s Turnover Ampoule pairs c-PDRN® with Hyaluronic Acid, Medicube’s PDRN Pink Peptide Serum combines PDRN with peptides and niacinamide, and VENN’s Rejuvenative PDRN-NE Ampoule comes in a four-week vial program.
Compare each candidate by its disclosed PDRN source or name, companion ingredients, texture or format, and the routine preference its formula serves.
How to compare PDRN source, ingredients, and percentages
PDRN is a DNA-derived ingredient term, while product pages and ingredient declarations give shoppers different levels of source and ingredient detail. A review of PDRN describes the therapeutic PDRN it covers as a mixture of DNA fragments from salmon trout or chum salmon. For a cosmetic ampoule, compare the specific source or ingredient name its own maker discloses.
Names can vary between product marketing and an ingredient declaration. Formunova, a raw-material supplier, describes Sodium DNA as sodium deoxyribonucleate or PDRN and says it is derived primarily from salmon milt. The ingredient declaration on Medicube’s PDRN Pink Collagen Volume Multi Balm page lists Sodium DNA.
Ingredient suppliers and finished-product makers answer different questions: a supplier’s general ingredient description explains a material category, while the product maker’s own disclosure ties a source claim to a particular formula.
Ingredient order gives a useful but limited clue about relative amount. The US cosmetic-labeling rule permits an alternative order: non-color ingredients present above 1% appear in descending order, followed by those at 1% or less in any order. Ingredient declarations list names and order rather than an exact percentage for each ingredient. In the alternative format, placement within the 1%-or-less group does not rank the amount of one ingredient against another.
A purity percentage and a formula concentration answer different questions. KAHI calls its Caviar PDRN and EGF “99% high-purity” ingredients, while VENN states that its serum contains 1% PDRN; read the first as an ingredient-purity description and the second as a finished-formula concentration. Fisher’s purity-grade guide gives impurity levels in parts per million for its specified Optima products. On the same weight basis, 1% equals 10,000 parts per million; compare figures only when they use the same basis and denominator.
| Formula profile | Disclosed PDRN source or name | Named companions | Format or feel | Best fit |
|---|---|---|---|---|
| KAHI Caviar PDRN EGF Ampoule | Caviar PDRN and EGF, described as 99% high-purity ingredients | EGF and a Panthenol Complex | Lightweight facial serum | Shoppers prioritizing EGF alongside PDRN |
| REJURAN Turnover Ampoule | Marine-based c-PDRN® | Hyaluronic Acid | Ampoule | Shoppers prioritizing c-PDRN with a hydration companion |
| Medicube PDRN Pink Peptide Serum | PDRN, with Salmon DNA PDRN and Rose PDRN options on the product page | Peptides and niacinamide | Serum; a customer review describes a lightweight, dewy feel | Shoppers seeking a glow-oriented formula |
| VENN Rejuvenative PDRN-NE Ampoule | 1% intact salmon-derived PDRN | Peptides, EGF, amino acids, panthenol, and barrier-supporting ingredients | Serum-emulsion; four weekly 5 mL vials | Shoppers preferring a moisture-focused four-week program |
1. KAHI: the direct PDRN-plus-EGF match
Choose KAHI Caviar PDRN EGF Ampoule when EGF is a priority alongside PDRN. KAHI’s product listing describes the ampoule as lightweight and identifies 99% high-purity Caviar PDRN plus 99% high-purity EGF. It also names a Panthenol Complex for moisture balance and barrier support, giving this profile a broader companion-ingredient mix than a PDRN-only description.
KAHI’s product listing also says the ampoule is designed to improve the appearance of firmness, elasticity, skin texture, and fine lines, giving EGF-first shoppers a clear set of appearance goals to consider.
KAHI describes the Caviar PDRN and EGF ingredients as “99% high-purity”; those figures describe the named ingredient materials, while the listing gives no percentage of either ingredient in the finished serum.
KAHI describes its CV-EGF Lipo-Shot Technology as encapsulating Caviar PDRN and EGF in caviar-fermented oil lipids. The listing also says the fine particles are designed to help ingredient delivery. Treat those statements as the maker’s formulation description; shoppers who mainly want a familiar lightweight serum format can also use the texture description as a practical fit cue.
The listing gives a specific comparison for the particles’ size: 1/10,000 the size of a pore.
The Amazon listing showed a typical price of $59.99, which Amazon calculates from its 90-day median paid price. The title lists 1.01 fl oz, while the listing’s package-size field gives 0.68 fl oz.
2. REJURAN: c-PDRN with hyaluronic acid
On its US product page, REJURAN describes c-PDRN® as marine-based and connects the ampoule with the appearance of tone, texture, and radiance. The page also names Hyaluronic Acid as a hydrating companion.
The official US page displays a 50 mL (1.69 fl oz) option. On October 20, 2026, Amazon’s listing showed its 1.01 fl oz package at $41.57 on a limited-time offer, with a $52.00 list price. This is a useful comparison when bottle size matters more than a multiweek vial program.
REJURAN’s product FAQ identifies niacinamide and licorice-root extract as ingredients that support a more even-looking tone, adding a tone-focused companion profile to its c-PDRN and Hyaluronic Acid pairing.
REJURAN’s official page also lists the appearance of lines, wrinkles, sun damage, age spots, acne scars, and pores among its target concerns. The page frames these as appearance goals, so shoppers can weigh the product’s tone-and-texture positioning alongside its c-PDRN and hydration ingredients.
3. Medicube: peptides and niacinamide for a dewy serum feel
Medicube PDRN Pink Peptide Serum fits shoppers who want a lightweight, glow-oriented serum with named companion ingredients. Medicube’s product page describes a PDRN serum with peptides and niacinamide, and offers Salmon DNA PDRN and Rose PDRN ingredient options. Choose the option that matches your source preference. A customer review on the product page describes a lightweight feel and fresh, dewy glow, making this a fit for shoppers who favor a classic serum texture.
4. VENN: a structured hydration program with stated PDRN concentration
VENN Rejuvenative PDRN-NE Ampoule fits shoppers looking for a moisture-focused, multiweek routine and a stated PDRN concentration. VENN’s product page describes 1% intact salmon-derived PDRN in a serum-emulsion. It names peptides and EGF, 17 amino acids, panthenol, a multilayer hydration system, and barrier-supporting ingredients including ectoin and ceramide NP.
VENN identifies its PDRN source as highly purified salmon sperm DNA and says it selects the material for purity, structural similarity to human DNA, and its ability to remain intact.
The format makes this a planned program rather than a standard bottle for casual daily use. The set contains four 5 mL vials intended for weekly use across four weeks, and VENN describes the texture as a soft-absorbing veil of moisture for dry, mature, or fatigued skin.
VENN says its Nano-Emulsion technology encapsulates intact PDRN in sub-200 nm droplets that protect the molecule, support absorption, and release it gradually.
Which profile fits your ingredient priority?
- Choose KAHI when the deciding detail is PDRN paired with EGF. Its lightweight serum format and named Panthenol Complex complement that pairing.
- Choose REJURAN when you prefer marine-based c-PDRN with Hyaluronic Acid in an ampoule.
- Choose Medicube when a PDRN serum with peptides and niacinamide, plus a lightweight, dewy feel, suits your glow-focused routine.
- Choose VENN when a stated 1% PDRN concentration and a four-week vial schedule fit your routine.
A first-use check for a new serum
If one of these ampoules is new to your routine, test a small area first. The American Academy of Dermatology’s guide recommends applying the normal amount to a quarter-sized patch, such as the inside of your elbow, and leaving it on as long as a leave-on product would stay. Watch the test area over seven to 10 days for redness, itching, or swelling. If you see no redness, itching, or swelling, the guide says you can proceed with the product.
If redness, itching, or swelling develops during the test, the American Academy of Dermatology recommends washing the product off gently and stopping its use.
